Former US public health official Anthony Fauci invoked the Fifth Amendment during a Republican-led Senate committee hearing focused on the origins of COVID-19 and the government’s handling of the pandemic. By doing so, Fauci declined to answer questions put to him at the hearing.

The Fifth Amendment is a constitutional protection that allows a person to refuse to give testimony that could be used against them in a criminal case. In practical terms, invoking it means a witness chooses not to respond to certain questions rather than risk self-incrimination.

Republicans used the hearing to press Fauci over pandemic-era decisions and the broader debate around how COVID-19 began and how officials responded. Fauci, who became one of the most visible faces of the US public health response, has remained a central figure in political arguments over lockdowns, messaging, and federal health policy.

His decision to invoke the amendment is likely to fuel further partisan debate. Supporters may view it as a legal safeguard available to any witness, while critics are likely to argue it raises more questions about accountability during the COVID-19 crisis.