The U.S. military said Saturday that two American troops were killed and a third service member is missing after Iran attacked a base in Jordan. The announcement points to a sharp escalation involving U.S. forces in the region.

According to the military, the troops were killed Friday. Officials said the deaths are the first suffered by U.S. personnel from direct Iranian fire since the opening days of the war, making the incident a significant turning point in the conflict.

The attack on the Jordan base is likely to deepen concerns about the safety of U.S. and partner forces operating across an increasingly volatile Middle East. It also adds pressure on Washington as it considers the implications of a strike that left American troops dead and another unaccounted for.

Only limited details were immediately available from the report, including the condition of the missing service member and any broader damage at the base. Even so, the military's statement signals a major development with potential regional consequences.