Andy Burnham is taking office as the United Kingdom’s new prime minister, succeeding Keir Starmer on Monday. While he may be less familiar to audiences outside Britain, his rise marks a major shift in the country’s political leadership.

Burnham is best known as the former mayor of Manchester, a role that tied him closely to politics in the north of England. That background is central to how he is understood politically, with his outlook shaped by the long-running economic and class divide between England’s north and south.

His move to Downing Street puts a politician associated with regional inequality and northern identity at the center of national power. Supporters and critics alike are likely to view his leadership through that lens as he begins his tenure.

As Burnham replaces Starmer, attention is turning to what his leadership could mean for the direction of British politics. His arrival signals not just a change in prime ministers, but also a change in the personal and regional story now driving the U.K. government.