The White House says federal agencies are committing more than $5 billion to the Genesis Mission, a major new push to use artificial intelligence to speed up scientific discovery. The effort is being led by the US Department of Energy and was presented by White House science adviser Michael Kratsios as part of a sweeping change in how the federal government supports research.

According to the announcement, the funding will support 278 AI-for-science projects. Those projects were chosen from more than 5,000 applications, pointing to strong demand across the research community for tools that can help scientists analyze data, model complex systems and move experiments forward faster.

The Genesis Mission is being framed as one of the biggest changes to federal science policy in decades. By directing large-scale funding toward AI-driven research, the administration is signaling that machine learning and related technologies are now central to how the government expects breakthroughs to happen in areas tied to national science priorities.

While full project details were not included in the initial summary, the scale of the investment shows how quickly AI is becoming embedded in public-sector research strategy. The program brings together multiple agencies behind a shared goal: using advanced computing and artificial intelligence to accelerate the pace of discovery across the US scientific system.