Billionaire investor Bill Ackman is moving beyond Wall Street with a major science project in New York City. According to Fortune, Ackman plans to spend $260 million to establish a large brain research institute in Manhattan, a venture reportedly shaped by a crisis in his family.

The planned facility will rise on the Upper West Side, where Ackman has recently bought two buildings for the project. The institute is expected to span about 700,000 square feet, making it a significant new presence for brain and neuroscience research in the city.

The effort marks a notable shift for Ackman, who is best known for high-profile and often contrarian investment bets. Instead of finance, this initiative is focused on supporting research tied to the brain, suggesting a long-term commitment to scientific work with potential medical and academic importance.

With its scale, location, and funding, the planned Manhattan institute could become a prominent center for brain research. The project also highlights how personal experiences can shape large philanthropic and scientific investments, especially in areas tied to health and discovery.