Researchers say a new study has clarified how infection with Epstein-Barr virus may set off the kind of immune response seen in multiple sclerosis, a chronic disease that affects the central nervous system. The work was published Wednesday in Science Translational Medicine.

According to the study, the virus appears to launch immune activity that is tied to the inflammation associated with multiple sclerosis. That helps address a long-running scientific question about how Epstein-Barr, which has been linked to MS in previous research, could contribute to the disease process.

The findings point to a biological pathway connecting viral infection with the immune reactions involved in multiple sclerosis. In broad terms, the research suggests that Epstein-Barr does more than show an association with MS — it may help drive the inflammatory responses that affect the nervous system.

While the report adds detail to the proposed connection between Epstein-Barr virus and multiple sclerosis, it represents another step in understanding the disease rather than a final answer. Even so, the study offers new insight into how a common viral infection could play a role in one of the most closely studied autoimmune-related neurological conditions.